Functional characterization of signaling molecules involved in neural-immune interaction


The nervous systems and immune systems are actively communicating in maintaining body homeostasis. We are interested in how these two systems interact to achieve their physiological functions. Specifically, we would like to explore the cellular and molecular mechanism of neural-immune interaction, focusing on which cell types are involved, which signal molecules are used for communication, and how these processes are regulated in different status and altered during diseases.

Our current projects include:
1、The purinergic signals in mediating brain injury response .
2、The neural-immune interaction in skin diseases.
Left: Astrocyte calcium wave imaged by genetically-encoded calcium indicators.     
Right: The dynamics of the extracellular signal "X" after laser induced brain injury in vivo.