Our first paper is now online in Nature Methods!


Although the ACh was the first identified neurotransmitter, its detail function and regulation in the complex nervous system is still a mystery. In collaboration with Li lab, we engineered and optimized the new ACh fluorescent sensor, ACh3.0, with the ability to sensitive and selective track cholinergic signals in vivo. We will be more than happy to share our sensors and collaborate with you to further understand ACh in the brain!